Helix session report

EXPLORATORY_UNCALIBRATED

Governance

governance_decision_mode: filter_only
governance_interpretation: exploratory_uncalibrated

Limitations

Guide

Guide: EMX1_g1 Target: Edit type:

Repair model

Outcome summary

Data artifacts

Guide metadata

{
  "cut_index": 19,
  "guide_id": "EMX1_g1",
  "run_id": 0
}

Run metadata

No run metadata provided.

Session metadata

{
  "limitations": {
    "banner": "Limitations apply: CRISPR Edit DAG model is not validated for kinetic or safety-critical prediction.",
    "doc_last_updated": "2025-12-26",
    "doc_slug": "crispr_edit_dag_limitations",
    "doc_url": "https://omniscoder.github.io/Helix/model_limitations/crispr_edit_dag_limitations/",
    "doc_version": "1.0",
    "timestamp_utc": "2025-12-31T16:02:08.761058Z"
  },
  "run_id": 0
}

Outcomes (JSON)

[
  {
    "E_pred": null,
    "category": "small_insertion",
    "delta_bp": 1,
    "flap_ddG": null,
    "frameshift": false,
    "microhomology": null,
    "name": "intended_edit",
    "pbs_dG": null,
    "peak_position": 0.5,
    "position_max": 20,
    "position_min": 19,
    "prob": 0.38
  },
  {
    "E_pred": null,
    "category": "no_cut",
    "delta_bp": 0,
    "flap_ddG": null,
    "frameshift": false,
    "microhomology": null,
    "name": "no_cut",
    "pbs_dG": null,
    "peak_position": 0.5,
    "position_max": 20,
    "position_min": 19,
    "prob": 0.26
  },
  {
    "E_pred": null,
    "category": "small_deletion",
    "delta_bp": -3,
    "flap_ddG": null,
    "frameshift": true,
    "microhomology": null,
    "name": "frameshift_del",
    "pbs_dG": null,
    "peak_position": 0.5,
    "position_max": 20,
    "position_min": 19,
    "prob": 0.22
  },
  {
    "E_pred": null,
    "category": "large_deletion",
    "delta_bp": -12,
    "flap_ddG": null,
    "frameshift": true,
    "microhomology": null,
    "name": "microhomology_del",
    "pbs_dG": null,
    "peak_position": 0.5,
    "position_max": 20,
    "position_min": 19,
    "prob": 0.14
  }
]

Top outcomes (CSV)

# limitations_banner: Limitations apply: CRISPR Edit DAG model is not validated for kinetic or safety-critical prediction.
# limitations_doc: crispr_edit_dag_limitations@1.0
# limitations_last_updated: 2025-12-26
# limitations_timestamp_utc: 2025-12-31T16:02:08.761058Z
# limitations_url: https://omniscoder.github.io/Helix/model_limitations/crispr_edit_dag_limitations/
# governance_decision_mode: filter_only
# governance_interpretation: exploratory_uncalibrated
name,category,prob,delta_bp,frameshift,peak_position,position_min,position_max,microhomology,pbs_dG,flap_ddG,E_pred
intended_edit,small_insertion,0.38,1,False,0.5,19,20,,,,
no_cut,no_cut,0.26,0,False,0.5,19,20,,,,
frameshift_del,small_deletion,0.22,-3,True,0.5,19,20,,,,
microhomology_del,large_deletion,0.14,-12,True,0.5,19,20,,,,